The chemical composition, antimicrobial and antioxidant activities of the essential oil of Salvia fruticosa growing wild in Libya

Autor: Giweli Abdulhamid A., Džamić Ana M., Soković Marina, Ristić M.S., Janaćković P., Marin P.D.
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Archives of Biological Sciences, Vol 65, Iss 1, Pp 321-329 (2013)
Druh dokumentu: article
ISSN: 0354-4664
1821-4339
DOI: 10.2298/ABS1301321G
Popis: The composition of essential oil isolated from Salvia fruticosa, wild growing in Libya, was analyzed by GC and GC-MS. Forty-five compounds could be identified. The essential oil contained 1,8-cineole (49.34%), camphor (7.53%), β-pinene (7.38%), myrcene (7.38%), α-pinene (5.15%), β-caryophyllene (4.13%) and α-terpineol (3.25). Antioxidant activity was analyzed using the DPP H free radical scavenging method and low antioxidant activity was found (IC50 = 15.53 mg/ml). The oil was also screened for its antimicrobial activity against eight bacteria (four Gram-negative and four Gram-positive) and eight fungi. The essential oil of S. fruticosa showed minimal inhibitory activity (MIC) at 0.125-1.5 mg/ml and bactericidal (MBC) at 0.5-2.0 mg/ml. In addition, it exhibited fungistatic (MIC) at 0.125-1.0 mg/ml and fungicidal effect (MFC) at 0.125-1.5 mg/ml. [Projekat Ministarstva nauke Republike Srbije, br. 173029 and br. 173032]
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