Age- and sex-related changes in hematological parameters in healthy Malawians

Autor: Mandala WL, Gondwe EN, MacLennan JM, Molyneux ME, MacLennan CA
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Journal of Blood Medicine, Vol Volume 8, Pp 123-130 (2017)
Druh dokumentu: article
ISSN: 1179-2736
Popis: Wilson L Mandala,1–3 Esther N Gondwe,1 Jenny M MacLennan,1,4 Malcolm E Molyneux,1,5 Calman A MacLennan1,6,7 1The Malaria Immunology Group, Malawi-Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Blantyre, Malawi; 2Biomedical Sciences Department, College of Medicine, Blantyre, Malawi; 3Biomedical Sciences Department, Academy of Medical Sciences, Malawi University of Science and Technology, Thyolo, Malawi; 4Department of Zoology, University of Oxford, Oxford, UK; 5Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; 6The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK; 7Institute of Immunology and Immunotherapy, College of Medicine and Dental Sciences, University of Birmingham, Birmingham, UK Aim: The aim of the study was to determine how values for white blood cell (WBC) counts, hemoglobin (Hb), hematocrit (Hct), mean corpuscular volume (mcv), and platelet counts vary with age and sex in healthy Malawians. Methods: We recruited 660 (316 male and 344 female) participants in 12 different age groups. An ethylenediaminetetraacetic acid-anticoagulated blood sample collected from each participant was analyzed using a hematological analyzer.Results: WBC counts decreased with age with the lowest counts observed in the 20 to
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