An updated review of cribriform carcinomas with emphasis on histopathological diagnosis and prognostic significance
Autor: | Giovanni Branca, Antonio Ieni, Valeria Barresi, Giovanni Tuccari, Rosario Alberto Caruso |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Oncology Reviews, Vol 11, Iss 1 (2017) |
Druh dokumentu: | article |
ISSN: | 1970-5557 1970-5565 |
DOI: | 10.4081/oncol.2017.317 |
Popis: | Cribriform is a histopathological term used to describe a neoplastic epithelial proliferation in the form of large nests perforated by many quite rounded different-sized spaces. This growth pattern may be seen in carcinomas arising in different organs, and shows important prognostic implications. Therefore, recent data in literature suggest that cribriform carcinoma is a histologically and clinically distinctive type of tumour that should be separated from other similar tumour types. In this article, the pathology of cribriform adenocarcinoma of the prostate, lung, breast, stomach, colon, thyroid, and skin is discussed with particular reference to morphologic and immunohistochemical features, differential diagnosis, and clinical behaviour. |
Databáze: | Directory of Open Access Journals |
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