Short-term air pollution exposure decreases lung function: a repeated measures study in healthy adults

Autor: Luc Int Panis, Eline B Provost, Bianca Cox, Tijs Louwies, Michelle Laeremans, Arnout Standaert, Evi Dons, Luc Holmstock, Tim Nawrot, Patrick De Boever
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Environmental Health, Vol 16, Iss 1, Pp 1-7 (2017)
Druh dokumentu: article
ISSN: 1476-069X
DOI: 10.1186/s12940-017-0271-z
Popis: Abstract Background Daily changes in ambient concentrations of particulate matter, nitrogen oxides and ozone are associated with increased cardiopulmonary morbidity and mortality, with the lungs and their function being a vulnerable target. Methods To evaluate the association between daily changes in air pollution and lung function in healthy adults we obtained annual lung function measurements from a routine worker health surveillance program not designed for research purposes. Forced Vital Capacity (FVC), Forced Expiratory Volume in the first second (FEV1), FEV1/FVC and Peak Expiratory flow (PEF) from a cohort of 2449 employees were associated with daily measurements of PM10, NO2 and ozone at a nearby monitoring station in the North of Belgium. Repeated measures were available for the period 2011–2015. Results The mean (SD) PM10 concentration on the day of the lung function test was 24.9 (15.5) μg/m3. A 10 μg PM10/m3 increase on the day of the clinical examination was associated with a 18.9 ml lower FVC (95% CI: -27.5 to −10.3, p
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