| Autor: |
Se Jik Han, Polina Belousova, Sangwoo Kwon, Jihui Jang, Jun Bae Lee, Hyunjae Kim, Gayeon You, Jihyeon Song, Hyejung Mok, Ho Su Ha, So Jeong Bae, In Jin Ha, Min Young Lee, Kyung Sook Kim |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Chemical and Biological Technologies in Agriculture, Vol 11, Iss 1, Pp 1-17 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2196-5641 |
| DOI: |
10.1186/s40538-024-00653-2 |
| Popis: |
Abstract Background Rose flowers contain active ingredients such as flavonoids and volatile oils and are acknowledged to be good natural resources owing to their anti-aging and antioxidant properties. In this study, we develop four new rose varieties (named Ever-rose) that are fragrant, pest resistant, and easy to grow. Subsequently, we evaluate the properties of Ever-rose and its potential for use in anti-aging products. Methods The chemical composition of Ever-rose was determined using ultra-high-performance liquid chromatography triple time-of-flight mass spectrometry/mass spectrometry. The antioxidant activity of the Ever-rose extract was evaluated using various assays, including superoxide dismutase activity, 2,2-diphenyl-1-picrylhydrazyl radical-scavenging capacity, and xanthine oxidase activity. The variations in proteolytic matrix metalloproteinase-1 expression, collagen content after ultraviolet (UV) irradiation, and reactive-oxygen-species (ROS) levels after infrared A (IRA) treatment were evaluated. The variations in cell elasticity were assessed via atomic force microscopy. Results The petal extracts of Ever-rose (named ER004(P), ER011(P), ER012(P), and ER015(P)) showed good antioxidant activity. They effectively inhibited UV irradiation-induced MMP-1 expression and IRA irradiation-induced increase in mitochondrial ROS levels. Additionally, they inhibited variations in cell shape and elasticity as aging progressed. In particular, ER011(P) demonstrated the best anti-aging and antioxidant effects. Conclusion The newly developed Ever-rose showed excellent antioxidant and anti-aging effects. In particular, ER011(P) demonstrated the best properties owing to its high antioxidant content. Hence, it exhibits significant potential as a functional cosmetic ingredient. Graphical Abstract |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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