Post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery

Autor: Keishi Sugino, Hirotaka Ono, Shuji Haraguchi, Seiji Igarashi, Akira Hebisawa, Eiyasu Tsuboi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Respirology Case Reports, Vol 9, Iss 12, Pp n/a-n/a (2021)
Druh dokumentu: article
ISSN: 2051-3380
DOI: 10.1002/rcr2.871
Popis: Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2, has become a global pandemic. Many survivors of serious COVID‐19 pneumonia have long‐term residual pulmonary disease. However, there is little documentation of the histopathological characteristics of lung sequelae post‐COVID‐19 and effective treatments. We present two Japanese cases of lung sequelae post‐COVID‐19. The patients were histopathologically diagnosed with organizing pneumonia (OP) or OP with fibrosis and no diffuse alveolar damage on video‐assisted thoracoscopic surgery. Case 1, who had been diagnosed with OP, was successfully treated with corticosteroid and other immunosuppressive agents over a 6‐month period. Although case 2, who had been diagnosed with OP with fibrosis, had a partial and unsatisfactory response to immunosuppressive agents, the patient responded to antifibrotic treatment including nintedanib.
Databáze: Directory of Open Access Journals