Cholestasis as the initial presentation of relapsing polychondritis

Autor: Maria da Graça Ferronato, Leonardo Jönck Staub, Renata Cristina Teixeira Pinto Viana, Lígia da Rosa, Maria Beatriz Cacese Shiozawa, Janaína L. Narciso-Schiavon, Esther Buzaglo Dantas-Correa, Leonardo de Lucca Schiavon
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Annals of Hepatology, Vol 10, Iss 4, Pp 565-567 (2011)
Druh dokumentu: article
ISSN: 1665-2681
DOI: 10.1016/S1665-2681(19)31528-5
Popis: Relapsing polychondritis is an immune-mediated disease associated with inflammation in cartilaginous structures and other tissues throughout the body, particularly the ears, nose, eyes, joints, and respiratory tract. Although association with other conditions is seen in about one-third of the cases, liver involvement is not usually observed in those patients. We described a case of liver involvement in relapsing polychon-dritis, presenting with a predominantly cholestatic pattern. Other conditions associated with abnormal liver tests were excluded and the patient showed a prompt response to steroid therapy. We discuss the spectrum of the liver involvement in relapsing and review the literature.
Databáze: Directory of Open Access Journals