Impact of COVID‐19 on the distribution of pathogenic bacteria in the lower respiratory tract of the elderly

Autor: Shi‐Yan Zhang, Jing Shi, Ying Zhuo, Ting‐Qiang Wang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Immunity, Inflammation and Disease, Vol 11, Iss 7, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2050-4527
DOI: 10.1002/iid3.931
Popis: Abstract Background To investigate the distribution of bacterial pathogens of lower respiratory tract infection (LRTI) in hospitalized elderly patients during the COVID‐19 epidemic and to explore the influence of COVID‐19 on the distribution of bacterial pathogens, to provide guidance for clinical diagnosis. Methods Specimens of sputum from elderly LRTIs patients at Fuding Hospital of China were consecutively collected from October 2022 to January 2023. Cultures and identification were done, and RT‐PCR was employed to detect SARS‐Cov‐2 nucleic acid. Results A total of 195 isolates were characterized in 163 sputum samples of consecutive hospitalized elderly patients, of which 11.3% were Gram‐positive bacteria and 88.7% were Gram‐negative. The top of frequently isolated pathogens was Klebsiella pneumonia (30.3%), Pseudomonas aeruginosa (19.0%), Acinetobacter baumannii (12.8%), Stenotrophomonas maltophili, (7.7%), Escherichia coli (7.2%). According to the results of novel coronavirus nucleic acid detection, the 163 patients were divided into COVID‐19 group and non‐COVID control (CNT) group. The comparison of bacterial distribution between the groups revealed that Stenotrophomonas maltophilia was lower in the COVID‐19 than in the CNT group, while A. baumannii was higher in the COVID‐19 group, and the difference was statistically significant (p
Databáze: Directory of Open Access Journals
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