The influence of cytotoxic drugs on the immunophenotype of blast cells in paediatric B precursor acute lymphoblastic leukaemia

Autor: Prelog Tomaz, Bucek Simon, Brozic Andreja, Peterlin Jakob, Kavcic Marko, Omerzel Masa, Markelc Bostjan, Jesenko Tanja, Prevodnik Veronika Kloboves
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Radiology and Oncology, Vol 58, Iss 1, Pp 133-144 (2024)
Druh dokumentu: article
ISSN: 1581-3207
DOI: 10.2478/raon-2024-0006
Popis: Flow cytometry plays is important in the diagnosis of acute lymphoblastic leukaemia (ALL) and when antigen-specific immunotherapy is indicated. We have investigated the effects of prednisolone, vincristine, daunorubicin, asparaginase and methotrexate on the antigen expression on blast cells that could influence the planning of antigen-specific therapy as well as risk-based treatment assignment.
Databáze: Directory of Open Access Journals