| Autor: |
Zhao-Guo Li, Bai-Cun Li, Zhi-Wei Li, Hui-Yuan Hu, Xia Ma, Hong Cao, Zhi-Hua Yu, Hua-Ping Dai, Jing Wang, Chen Wang |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Journal of Immunology Research, Vol 2023 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2314-7156 |
| DOI: |
10.1155/2023/9233386 |
| Popis: |
Evidence suggests that exposure to coal dust increases immunoglobulin concentration. However, there is a paucity of data reporting immunoglobulin G (IgG) subclass in coal workers’ pneumoconiosis (CWP). Therefore, this study intended to evaluate potential diagnostic biomarkers for the disease. CWP patients, dust-exposed workers without pneumoconiosis (DEW), and matched healthy controls (HCs) presented to the General Hospital of Datong Coal Mining Group and Occupational Disease Prevention and Treatment Hospital of Datong Coal Mining Group between May 2019 and September 2019 were recruited. The serum immunoglobulin concentration was determined by the multiplex immunoassay technique. Totally, 104 CWP patients, 109 DEWs, and 74 HCs were enrolled. Serum levels of IgG1, IgG2, IgM, and IgA were elevated in CWPs compared with those in DEWs and HCs (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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