FUNCTIONAL ACTIVITY OF COMPLEMENT CLASSIC WAY ACTIVATION COMPONENTS AND ART1CULAS DAMAGE IN RHEUMATOID ARTRITIS
| Autor: | D. L. Goryachev, T. V. Lebedeva |
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| Jazyk: | ruština |
| Rok vydání: | 2000 |
| Předmět: | |
| Zdroj: | Научно-практическая ревматология, Vol 38, Iss 1, Pp 31-34 (2000) |
| Druh dokumentu: | article |
| ISSN: | 1995-4484 1995-4492 |
| DOI: | 10.14412/1995-4484-2000-784 |
| Popis: | A relationship between X - ray joints changes and functional activity of classical pathway complement components in R4 was investigated. 31 patients with the moderate activity ofRA (ARA 1987) have been examined. Disease duration was 4,5lyear±3,84 (SD). X-ray stage was estimated by Steinbrocker (I-II-III-IV). II patients were in II stage, 8 in III stage, 12 in IV-stage. Concentration of C3 and C4 components have been evaluated by radial immunodiffuision, functional activity of complement components (Clq. C1-C5) - using a microhemolilical systems. High correlation values between functional activity C1-C4 complement components and X-ray stage of disease were obtained (Spearman correlation: 0,38 |
| Databáze: | Directory of Open Access Journals |
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