Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report

Autor: German E. Ramos, Christian Caglevic, Juan F. Bulnes, Sergio E. Panay, Mario I. Zapata, Andrés J. Daniele, Manuel E. Rodríguez
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Druh dokumentu: article
ISSN: 2297-055X
DOI: 10.3389/fcvm.2022.1060813
Popis: Endothelial Growth Factor Receptor (EGFR) mutations are frequently found among NSCLC patients. Second-generation Tyrosine Kinase Inhibitor (TKI) Afatinib is frequently used in this population of patients achieving better results than cytotoxic chemotherapy in terms of survival and progression. Afatinib-related cardiotoxicity has been rarely reported. Here we comment on a clinical case of a Takotsubo Cardiomyopathy Afatinib-induced in an NSCLC patient.
Databáze: Directory of Open Access Journals