Central airway squamous metaplasia following radiation therapy mimicking local tumour recurrence

Autor: Jonathan Arulanantham, Revadhi Chelvarajah, A Kasim Ismail, Victoria J. Bray, Shalini K. Vinod, Jonathan P. Williamson
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 46, Iss , Pp 101942- (2023)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2023.101942
Popis: Radiation therapy can result in injury to the lung parenchyma and central airways; the latter is less well documented in the literature. Here, we describe a 65-year-old Caucasian male, who developed focal endobronchial nodules and right main bronchial stenosis suggesting tumour recurrence, 32 months following curative intent concurrent chemoradiation therapy for Stage 3B squamous cell carcinoma of the lung. Computed tomography and positron emission tomography results are detailed. Flexible bronchoscopy with bronchial biopsies revealed squamous metaplasia rather than malignant tumour recurrence, with ongoing observation planned.
Databáze: Directory of Open Access Journals