A retrospective analysis of intraocular pressure changes after cataract surgery with the use of prednisolone acetate 1% versus difluprednate 0.05%

Autor: Kusne Y, Kang P, Fintelmann RE
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Clinical Ophthalmology, Vol Volume 10, Pp 2329-2336 (2016)
Druh dokumentu: article
ISSN: 1177-5483
Popis: Yael Kusne,1 Paul Kang,1 Robert E Fintelmann1,2 1University of Arizona College of Medicine–Phoenix, 2Barnet Dulaney Perkins Eye Center, Phoenix, AZ, USA Purpose: To compare the effect of topical prednisolone acetate 1% (PA) used after routine cataract surgery to the effect of difluprednate 0.05% (DFBA) used for the same indication on intraocular pressure (IOP).Methods: An electronic query was created to gather information from all cataract surgeries between January 2010 and January 2015 within the electronic health record database at Barnet Dulaney Perkins, a multicenter, multiphysician private practice in Phoenix, Arizona. Information collected included age, sex, diabetes status, glaucoma history, medication regimen (use of PA or DFBA), and IOP before surgery, 5–10 days postoperatively (TP1) and 3–6 weeks postoperatively (TP2). Postoperative IOP measurements were compared to baseline IOP measurement in each patient.Results: Regardless of steroid used, all patients in this study experienced an increase in IOP within TP1 and returned to baseline IOP (±2.0 mmHg) by TP2. Patients who received DFBA showed a statistically significant increase in IOP at TP1 compared to those on PA (P75) (P
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