Unusual combination of gestational trophoblastic neoplasias: case report

Autor: Irina Dulce Tapadinhas Matos Ramilo, Gustavo Martins Mendinhos, Fernando Antônio Ferreira da Igreja, Maria Clara Morais Aleluia, Rosete Maria Amorim Novais Nogueira, Fernando Manuel Ribeiro Gomes, José Manuel Silva Pereira
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 50, Iss 5, Pp 375-378 (2014)
Druh dokumentu: article
ISSN: 1678-4774
1676-2444
DOI: 10.5935/1676-2444.20140044
Popis: Gestational trophoblastic disease comprises a heterogeneous group of lesions arising from abnormal proliferation of trophoblastic cells. An elevation of human chorionic gonadotropin after evacuation of a molar pregnancy should suggest the hypothesis of a persistent gestational trophoblastic neoplasia. We present a rare case of coexistence of choriocarcinoma and placental-site trophoblastic tumor in the same tumor, whose diagnosis was made based on the correlation of morphological, microscopic and immunocytochemical studies, due to the difficulty in diagnosing these mixed tumors based on conventional histology only.
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