Multiple ESBL-producing Escherichia coli sequence types carrying quinolone and aminoglycoside resistance genes circulating in companion and domestic farm animals in Mwanza, Tanzania, harbor commonly occurring plasmids

Autor: Jeremiah eSeni, Linda eFalgenhauer, Nabina eSimeo, Mariam M Mirambo, Can eImirzalioglu, Mecky eMatee, Mark eRweyemamu, Trinad eChakraborty, Stephen E Mshana
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Frontiers in Microbiology, Vol 7 (2016)
Druh dokumentu: article
ISSN: 1664-302X
DOI: 10.3389/fmicb.2016.00142
Popis: The increased presence of extended-spectrum beta-lactamase (ESBL)-producing bacteria in humans, animals and their surrounding environments is of global concern. Currently there is limited information on ESBL presence in rural farming communities worldwide. We performed a cross-sectional study in Mwanza, Tanzania, involving 600 companion and domestic farm animals between August/September 2014. Rectal swab/cloaca specimens were processed to identify ESBL-producing Enterobacteriaceae. We detected 130 (21.7%) animals carrying ESBL-producing bacteria, the highest carriage being among dogs and pigs [39.2% (51/130) and 33.1% (43/130), respectively]. The majority of isolates were Escherichia coli [93.3% (125/134)] and exotic breed type [OR (95%CI) = 2.372 (1.460 - 3.854), p-value
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