Haematological profile of adult sickle cell disease patients in North Maharashtra

Autor: A. J. Jadhav, S. M. Vaidya, V. R. Bhagwat, A. R. Ranade, M. Vasaikar
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Walawalkar International Medical Journal, Vol 3, Iss 1, Pp 28-36 (2017)
Druh dokumentu: article
ISSN: 2349-2910
2395-0684
Popis: Background: Sickle cell anaemia is a major genetic disease in India that presents major challenges to our health care systems. Aim and Objective: The aim of this study was to evaluate the haematological profile of Sickle Cell Disease (SCD) patients in the steady state from tribal population of North Maharashtra. Material & methods: Thirty six sickle cell disease patients in steady state, 43 sickle cell carriers and 43 normal healthy volunteers with age group18-40 years were recruited for the study. Subjects having history of vaso-occlussive crisis, blood transfusion and serious illness within last three months were excluded from the study. Results: We found low levels of haemoglobin 7.86 ± 1.93gm/dl, Red Blood Cell count 2.93 ± 0.73 milli/cmm, as well as the Packed Cell Volume 27.18 ± 5.35% in the male and female SCD patients when compared with the carriers and normal subjects. Mean Corpuscular Volume 93.91 ± 6.9 was found to be higher whereas Mean Corpuscular Haemoglobin Concentration 28.71 ± 2.19 values were less (P
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