Bladder Cancer Invading the Prostate and Penis and Multiple Bone Metastases Showing Significant Improvement after a Short-Term Pembrolizumab Therapy following Radiation and Gemcitabine and Cisplatin Therapy Leading to a Pathologically Complete Remission

Autor:	Kyohei Ishida, Akira Ogose, Gen Kawaguchi, Go Hasegawa, Yohei Ikeda, Noboru Hara, Tsutomu Nishiyama
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Diseases of the genitourinary system. Urology RC870-923
Zdroj:	Case Reports in Urology, Vol 2024 (2024)
Druh dokumentu:	article
ISSN:	2090-6978
DOI:	10.1155/2024/7525757
Popis:	A 65-year-old man was diagnosed with bladder cancer invading the prostate and penis and multiple bone metastases. He underwent palliative radiation (30 Gy/10 fr) through vertebral bones (Th3 and Th12-L5) and pelvic bones for pain control. The patient received pembrolizumab therapy after three courses of gemcitabine and cisplatin therapy. CT four weeks after starting pembrolizumab therapy showed that both the primary and metastatic lesions had notably reduced in size, and no new lesion was detected. He subsequently fell, resulting in a femoral neck pathological fracture, and underwent hemiarthroplasty. Pathological examination of the pathological fracture site revealed no residual tumor tissue.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/82035375c6f248af85eb47d25b4c81fa Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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