| Autor: |
Alois Gratwohl, Anna Sureda, Helen Baldomero, Michael Gratwohl, Peter Dreger, Nicolaus Kröger, Per Ljungman, Eoin McGrath, Mohamad Mohty, Arnon Nagler, Alessandro Rambaldi, Carmen Ruiz de Elvira, John A. Snowden, Jakob Passweg, Jane Apperley, Dietger Niederwieser, Theo Stijnen, Ronald Brand |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
EBioMedicine, Vol 2, Iss 12, Pp 2101-2109 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
2352-3964 |
| DOI: |
10.1016/j.ebiom.2015.11.021 |
| Popis: |
Hematopoietic stem cell transplantation (HSCT) is a lifesaving expensive medical procedure. Hence, more transplants are performed in more affluent countries. The impact of economic factors on patient outcome is less defined. We analyzed retrospectively a defined cohort of 102,549 patients treated with an allogeneic (N = 37,542; 37%) or autologous (N = 65,007; 63%) HSCT. They were transplanted by one of 404 HSCT centers in 25 European countries between 1999 and 2006. We searched for associations between center-specific microeconomic or country-specific macroeconomic factors and outcome. Center patient-volume and center program-duration were significantly and systematically associated with improved survival after allogeneic HSCT (HR 0·87; 0·84–0·91 per 10 patients; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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