The morphology of unipolar potentials predicts the depth of activation foci

Autor: Yoshiaki Kaneko, MD, PhD, Tadashi Nakajima, MD, PhD, Masahiko Kurabayashi, MD, PhD
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Journal of Arrhythmia, Vol 30, Iss 4, Pp 292-299 (2014)
Druh dokumentu: article
ISSN: 1880-4276
DOI: 10.1016/j.joa.2014.02.009
Popis: Background: The depth of an arrhythmic focus is a major determinant of ablation procedural outcome. This study examined the relationship between the morphology of unipolar potentials and the depth and horizontal distance to activation foci. Methods: Unipolar left ventricular epicardial mapping was performed in 7 open-chest dogs, using silicon sheets with 12 unipolar electrodes 1 mm apart, during bipolar pacing from an octopolar plunge electrode with 1-mm interelectrode spacing. The morphology of the unipolar electrograms was classified as QS, rS, qrS, qRS, rsr’S, or rsR’S. Results: A QS complex was recorded immediately above a subepicardial or mid-myocardial pacing site. An rS complex was recorded away from a subepicardial pacing site. A positive wave originating from a down sloping deflection (R-in-QR) such as r wave in qrS, R wave in qRS, r′ wave in rsr’S or R′ wave in rsR’S complexes was observed when the recording was above a deep myocardial pacing site or away from a mid-myocardial pacing site. The amplitude of negative wave immediately before R-in-QR (Q-in-QR) was inversely correlated with the horizontal (R=−0.40; P
Databáze: Directory of Open Access Journals