Effects of noise stress on thyroid gland histomorphology in adult rats

Autor: Saba Saleem Safdar, Khadija Qamar, Mehwish Abaid, Muhammad Fahad Atta, Muhammad Sabir, Muhammad Rizwan Bashir Kiani
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Khyber Medical University Journal, Vol 16, Iss 2, Pp 165-70 (2024)
Druh dokumentu: article
ISSN: 2305-2643
2305-2651
DOI: 10.35845/kmuj.2024.23558
Popis: OBJECTIVE: To analyze the effects of variable durations of loud noise stress on the histomorphology of the thyroid gland in adult rats. METHODS: This laboratory-based experimental study was conducted at the Anatomy Department, Army Medical College/National University of Medical Sciences, Rawalpindi, Pakistan, from January to December 2020. Thirty Sprague Dawley rats were divided into three groups: Control group A (no noise exposure), experimental group B (100 dB noise for 4 hours daily), and experimental group C (100 dB noise for 6 hours daily) for four months. At the end of the experiment, the rats were weighed, euthanized, and their thyroid glands removed. The glands were analyzed microscopically after Haematoxylin and Eosin staining, measuring the diameter and epithelial height of thyroid follicles. RESULTS: All rats remained healthy with no statistically significant differences in weight gain between the groups. The follicular epithelial height significantly increased in groups B (9.86±0.38 µm) and C (10.37±0.39 µm) compared to the control group A, (p-values
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