Recent Advances in Organocatalyzed Domino C–C Bond-Forming Reactions

Autor: Cleo S. Evans, Lindsey O. Davis
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Molecules, Vol 23, Iss 1, p 33 (2017)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules23010033
Popis: Reactions that form a C–C bond make up a foundational pillar of synthetic organic chemistry. In addition, organocatalysis has emerged as an easy, environmentally-friendly way to promote this type of bond formation. Since around 2000, organocatalysts have been used in a variety of C–C bond-forming reactions including Michael and aldol additions, Mannich-type reactions, and Diels–Alder reactions, to name a few. Many of these methodologies have been refined and further developed to include cascade and domino processes. This review will focus on recent advances in this area with an emphasis on methodologies having applications in the synthesis of biologically-significant compounds.
Databáze: Directory of Open Access Journals
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