Manic-Like Psychosis Associated with Elevated Trough Tacrolimus Blood Concentrations 17 Years after Kidney Transplant

Autor:	Giuseppe Bersani, Pietropaolo Marino, Giuseppe Valeriani, Valentina Cuoco, Claudia Zitelli, Claudia Melcore, Francesco Saverio Bersani
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Psychiatry RC435-571
Zdroj:	Case Reports in Psychiatry, Vol 2013 (2013)
Druh dokumentu:	article
ISSN:	2090-682X 2090-6838 65608194
DOI:	10.1155/2013/926395
Popis:	Several neurological side effects induced by tacrolimus are described in the scientific literature, ranging from mild neurological symptoms to delirium and psychosis. We report the case of a 46-year-old man with no prior psychiatric history who suddenly manifested manic-like psychosis associated with elevated trough tacrolimus blood concentrations 17 years after kidney transplant. The use of antipsychotics may improve the severity of symptoms; but in order to obtain a complete remission, the reduction in the dose of tacrolimus, or its replacement with alternative immunosuppressant therapies, is recommended.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/81caf6560819419aba62966bb2ab4d75 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF