THE EFFECT OF LASER-ASSISTED HATCHING ON PREGNANCY OUTCOMES OF VITRIFICATION FROZEN EMBRYO TRANSFER

Autor: Vellyana Lie, Andri Rezano, Tono Djuwantono, Maitra Djiang Wen
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Majalah Biomorfologi, Vol 34, Iss 2, Pp 114-122 (2024)
Druh dokumentu: article
ISSN: 0215-8833
2716-0920
DOI: 10.20473/mbiom.v34i2.2024.114-122
Popis: Highlights • LAH might effectively increase pregnancy outcomes for frozen-thawed embryo transfer. • Zona pellucida drilling might help increase pregnancy outcomes in FET. Abstract Background: Zona Pellucida (ZP) thickness of less than 16 mm is better for embryo implantation inside the endometrium. Laser Assisted Hatching (LAH) is commonly used, especially in non-contact mode, using a 1.48-um infrared diode laser beam because of its short exposure time, accurate positioning, simple operation, indirect contact, safety, and effectiveness. Objective: This paper describes the potential of laser-assisted hatching in biochemical pregnancy outcomes in Frozen Embryo Thawed transfers. Material and Method: The total number of patients enrolled in this study was 141. Patients were prospectively treated during embryo transfers at Pusat Fertilitas Bocah Indonesia, Primaya Hospital at Tangerang, Indonesia, from December 2020 until December 2021. Result: There were no significant differences between the LAH and no-LAH groups regarding average age, infertility duration, infertility type, and etiology of infertility (p>0.05). In the same line, the blastocyst (0.76 ± 0.87; 1.25 ± 1.08) compared with cleavage (0.72 ± 0.84; 0.67 ± 0.98) (p
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