The histomorphological effect of Viola odorata flower extract on skin wound healing process in Wistar rats

Autor: Ehsan Sedghi, Elham Moghtadaei-Khorasgani, Mostafa Norbakhsh
Jazyk: perština
Rok vydání: 2020
Předmět:
Zdroj: Fiyz̤, Vol 24, Iss 4, Pp 366-373 (2020)
Druh dokumentu: article
ISSN: 1029-7855
2008-9821
Popis: Background: Wound healing is an important concern that humankind is facing and attempting to find compounds that have the least side effects on wound healing is important. Since violet flower extract has anti-inflammatory and disinfection effects, in this study the impact of this plant on wound healing was examined. Materials and Methods: 32 rats were provided from the laboratory animal breeding center in Shahrekord, and after anesthetizing them, a full-thickness skin wound was created by a 2 by 2 Cm stencil in the posterior cervical region. The control group received no treatment, one group received Eucerin, another group received Silver Sulfadiazine 1% and the experimental group received ointment of violet flower extract 20% twice a day. Throughout the study, the length and width of the wounds were measured in each group every three days. On the 3rd, 7th, 14th and 21st days after creating the wound, the rats were anesthetized and the healed tissues were examined for histopathologic studies. Results: The results showed a significant reduction in wound area in treated animals, especially violets, compared with the control group (P
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