Integrated transcriptome and proteome revealed that the declined expression of cell cycle-related genes associated with follicular atresia in geese

Autor: Wanli Yang, Xingyong Chen, Zhengquan Liu, Yutong Zhao, Yufei Chen, Zhaoyu Geng
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Genomics, Vol 24, Iss 1, Pp 1-17 (2023)
Druh dokumentu: article
ISSN: 1471-2164
DOI: 10.1186/s12864-022-09088-1
Popis: Abstract Background Geese exhibit relatively low reproductive performance, and follicular atresia is an important factor that restricts the egg production of geese. Systematic analysis of the regulation of follicle atresia in geese through transcriptome and proteome levels could provide meaningful information on clarifying the mechanism of follicle atresia in poultry. Result The granulosa cell layer was loose, disintegrated and showed apoptosis in atretic follicles and remained intact in normal follicles. The hormone levels of FSH and LH were significantly decreased in the atresia follicles compared to the normal follicles (P
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