Left atrioventricular interaction and impaired left atrial phasic function in type 2 diabetes mellitus patients with or without anemia: a cardiac magnetic resonance study

Autor: Wen-Lei Qian, Zhi-Gang Yang, Rui Shi, Ying-Kun Guo, Han Fang, Meng-ting Shen, Yuan Li
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 1475-2840
DOI: 10.1186/s12933-023-01910-8
Popis: Abstract Objective Type 2 diabetes mellitus (T2DM) and anemia are related to some cardiovascular diseases and can predict poor outcomes. Both of them can damage the heart in their own ways, but their combined effects have not been well explored. This study aimed to explore the combined effects of T2DM and anemia and the interaction between left atrial (LA) and left ventricular (LV) function by cardiac magnetic resonance (CMR). Materials and methods A total of 177 T2DM patients without anemia, 68 T2DM patients with anemia and 73 sex-matched controls were retrospectively enrolled in this study from June 2015 to September 2022. Their LA phasic function and LV function parameters were compared to explore the combined effects of T2DM and anemia and the interaction between LA and LV function. Univariate and multivariate linear regression were done to explore the independent factors influencing LA phasic function and LV function. Results Compared with controls and T2DM patients without anemia, T2DM patients with anemia were older and had higher heart rate, higher creatinine, lower estimated glomerular filtration rate (eGFR) and lower hemoglobin (Hb) (all p
Databáze: Directory of Open Access Journals
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