Psoas muscle quantified muscle status and long-term mortality after cardiovascular interventions

Autor: Otto Järvinen, Juho T. Tynkkynen, Marko Virtanen, Pasi Maaranen, Iisa Lindström, Damir Vakhitov, Jari Laurikka, Niku K. Oksala, Jussi A. Hernesniemi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Annals of Medicine, Vol 55, Iss 2 (2023)
Druh dokumentu: article
ISSN: 07853890
1365-2060
0785-3890
DOI: 10.1080/07853890.2023.2259798
Popis: AbstractBackground Psoas muscle area (PMA) and density (PMD) measured using computed tomography are potential surrogates for evaluating sarcopenia-related mortality risk among patients undergoing cardiovascular interventions. However, the optimal measurement method remains unclear.Methods A retrospective registry study of three observational cohorts comprising 2248 patients undergoing cardiovascular interventions (n = 828 for abdominal aortic aneurysms, n = 983 transcatheter aortic valve implantations, and 437 patients undergoing open surgery for thoracic aortic and aortic valve pathology) was conducted. Age-independent associations between mortality and PMA, PMD, PMA indexed to height or body surface area, and the combination of PMA and PMD (lean PMA) were meta-analyzed (using individual participant data) across cohorts after sex stratification with median follow-up times ranging from three to five years for each cohort.Results In the meta-analysis, psoas muscle measurements were significantly associated with mortality among men (p
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