Mechanical homeostasis of liver sinusoid is involved in the initiation and termination of liver regeneration

Autor: Jun Ishikawa, Makoto Takeo, Ayako Iwadate, Junko Koya, Miho Kihira, Masamitsu Oshima, Yuki Suzuki, Kazushi Taniguchi, Ayaka Kobayashi, Takashi Tsuji
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-021-01936-2
Popis: Ishikawa, Takeo et al. present a 3D liver sinusoidal network analysis method and identify important parameters after partial hepatectomy. They find that in coordination with cytokine networks, mechanical homeostatic signalling, including shear stress and tension, plays critical roles in the initiation and termination of liver organ regeneration.
Databáze: Directory of Open Access Journals