Autor: |
Xueqin Chen, Ning Dai, Yanyong Deng, Xin Sun, Mingqing Zhang, Jie Pan, Zhiming Huang, Guoliang Ye, Jianmin Si, Lan Wang, Shujie Chen |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-9 (2021) |
Druh dokumentu: |
article |
ISSN: |
1471-230X |
DOI: |
10.1186/s12876-021-01623-w |
Popis: |
Abstract Background The reformulated simethicone emulsion from Berlin Chemical AG might develop white flocculate precipitate covering the gastric mucosa when used before esophagogastroduodenoscopy (EGD). We aim to investigate whether combining the reformulated simethicone emulsion with 5% sodium bicarbonate solution could prevent the development of white precipitate and improve visibility during EGD. Methods Our clinical study involved 523 patients. They were randomly assigned to two groups. In Group A, patients received a warm solution containing 30 ml 5% sodium bicarbonate solution and 15 ml reformulated simethicone emulsion. In Group B, patients received 45 ml 40 °C lukewarm water. Visibility scores were recorded and analyzed. Flushes, volume of flush water, overall time taken for EGD and complications during or after the procedure were also recorded. Results We found that no white precipitate was observed during EGD in Group A. Moreover, visibility scores in Group A were significantly lower (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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