Rubella IgM epidemiology in the pre-rubella vaccination era in Uganda

Autor: Fred Bagenda, Edgar Mugema Mulogo, Richard Onyuthi Apecu, Anette Kisakye, Benard Toliva Opar
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-7 (2020)
Druh dokumentu: article
ISSN: 1471-2334
DOI: 10.1186/s12879-020-4928-9
Popis: Abstract Background Control of Rubella and Congenital Rubella Syndrome using vaccination has shown great success in the America’s. Uganda is due to introduce the Rubella vaccine however the magnitude of transmission is not well documented. Therefore this study was done to determine IgM sero-prevalance for Rubella in order to help monitor vaccine effectiveness post introduction of the vaccine in routine vaccination programme. Methods A retrospective review of suspected measles cases data for the reporting period January 2007 to December 2016 in Uganda was Done. rubella IgM testing was done on 15,296 of the cases and the data was analyzed using STATA version 13. Results In total 15,296 cases were tested and 4255 (27.8%) tested positive and among females aged 15-49 years 88 out of 322 (27%) tested positive. The age distribution range was 0–80 years, rubella IgM positivity was reported in all the 15 regions of Uganda and throughout the ten year period in every month. Age group 5–15 years had OR 2.5 p-value
Databáze: Directory of Open Access Journals
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