Comparison of the effect of Triticum Vulgare and Hyperici Oleum on healing in traumatic membrane perforation: an animal study

Autor: Adem Bora, Kasım Durmuş, Zeynep D.Şahin İnan, Berat Baturay Demirkıran, Emine E. Altuntas
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: The Egyptian Journal of Otolaryngology, Vol 39, Iss 1, Pp 1-8 (2023)
Druh dokumentu: article
ISSN: 2090-8539
DOI: 10.1186/s43163-023-00389-0
Popis: Abstract Background Traumatic tympanic membrane (TM) perforations usually heal spontaneously. The aim of this study was to investigate whether the topical application of Triticum Vulgare (TV) in experimentally induced traumatic TM perforations in the rats has a positive effect on wound healing process. Methods The rats were randomly assigned to four experimental groups. Drugs were introduced twice a day for 7 days. On the 7th day, specimens were sent for histological examination. Results Mean values found in group NC in terms of epithelial regeneration mean scores are as follows: fibroblast and collagen density, neovascularization, and density of inflammation cells were lower than all groups (p
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