Risk agents related to work and amyotrophic lateral sclerosis: An occupational medicine focus
| Autor: | Elpidio Maria Garzillo, Nadia Miraglia, Paola Pedata, Daniela Feola, Monica Lamberti |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | International Journal of Occupational Medicine and Environmental Health, Vol 29, Iss 3, Pp 355-367 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1232-1087 1896-494X |
| DOI: | 10.13075/ijomeh.1896.00368 |
| Popis: | Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscular paralysis reflecting degeneration of motor neurons. In recent years, in addition to several studies about genetic mechanisms leading to motor neurons damage, various epigenetic theories have been developed, involving the study of the patients’ work and lifestyle. The work aims at focusing the role of occupational exposure related to ALS by literature data analysis. Articles, selected on the basis of keywords, year of publication and topics, are related to occupational exposure, suggesting an impact on ALS onset. The literature review shows that there are still a lot of biases in the studies design, which actually do not allow to draw unequivocal conclusions. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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