Does SarsCoV-2 infection really cause damage to retinal microcirculation in mild cases of COVID-19?

Autor: Adisa Pilavdžić, Suzana Pavljašević, Amra Nadarević Vodenčarević, Anis Međedović, Meliha Halilbašić, Alma Čičkušić, Nejra Hodžić, Sumeja Terzić, Azra Šmigalović, Sanela Muhović
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Medicinski Glasnik, Vol 21, Iss 1, Pp 52-56 (2024)
Druh dokumentu: article
ISSN: 1840-0132
1840-2445
DOI: 10.17392/1633-23
Popis: Aim To evaluate changes of retinal microcirculation in mild cases of recovered COVID-19 patients at least three months after the infection by optical coherence tomography angiography (OCTA) non-invasive method. Methods In this prospective cross-sectional study, 50 right eyes of 50 recovered COVID-19 patients were compared with 50 right eyes of age and gender-matched healthy controls. After the complete ophthalmological examination, all participants underwent OCTA measurements (RTVue XR Avanti, Optovue, Fremont, CA, USA). Results The time between the initial onset of symptoms, and ophthalmologic examination was 479.20 ±197.10 (126-754) days. Findings of ophthalmic examination of all eyes of the recovered COVID-19 patients were within normal range. Significantly reduced superficial (p=0.046) and deep (p=0.044) macular vessel density (VD) in foveal region in the eyes of the recovered COVID-19 patients was found compared with healthy controls. Significantly enlarged foveal avascular zone (FAZ) area and perimeter in the eyes of the recovered COVID-19 patients (p
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