Accuracy, repeatability, and reproducibility of water-fat magnetic resonance imaging in a phantom and healthy volunteer

Autor: Anouk Corbeau, Pien van Gastel, Piotr A. Wielopolski, Nick de Jong, Carien L. Creutzberg, Uulke A. van der Heide, Stephanie M. de Boer, Eleftheria Astreinidou
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Physics and Imaging in Radiation Oncology, Vol 32, Iss , Pp 100651- (2024)
Druh dokumentu: article
ISSN: 2405-6316
DOI: 10.1016/j.phro.2024.100651
Popis: Bone marrow (BM) damage due to chemoradiotherapy can increase BM fat in cervical cancer patients. Water-fat magnetic resonance (MR) scans were performed on a phantom and a healthy female volunteer to validate proton density fat fraction accuracy, reproducibility, and repeatability across different vendors, field strengths, and protocols. Phantom measurements showed a high accuracy, high repeatability, and excellent reproducibility. Volunteer measurements had an excellent intra- and interreader reliability, good repeatability, and moderate to good reproducibility. Water-fat MRI show potential for quantification of longitudinal vertebral BM fat changes. Further studies are needed to validate and extend these findings for broader clinical applicability.
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