| Autor: |
Xuan Jiang, John S. Hawkins, Jerry Lee, Carlos O. Lizama, Frank L. Bos, Joan P. Zape, Prajakta Ghatpande, Yongbo Peng, Justin Louie, Giorgio Lagna, Ann C. Zovein, Akiko Hata |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-017-00137-y |
| Popis: |
Hematopoietic stem and progenitor cells are generated first from the vascular endothelium of the dorsal aorta and then the fetal liver but what regulates this switch is unknown. Here, the authors show that changing miRNA biogenesis and leukotriene B4 signaling in mice modulates this switch in the niche. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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