Cross-sectional and longitudinal associations of adherence to WCRF/AICR cancer prevention recommendations with health-related quality of life in breast cancer survivors. Health-EpiGEICAM study

Autor: Virginia Lope, Ángel Guerrero-Zotano, Nerea Fernández de Larrea-Baz, Silvia Antolín, Marta Benavent Viñuales, Begoña Bermejo, Emma Ruiz-Moreno, José Manuel Baena-Cañada, Lorena París, Antonio Antón, José Ignacio Chacón, Montserrat Muñoz, José Angel García-Sáenz, Clara Olier, Pedro Sánchez Rovira, Angels Arcusa Lanza, Sonia González, Joan Brunet, Amparo Oltra, Susana Bezares, Libertad Rosell, Beatriz Pérez-Gómez, Roberto Pastor-Barriuso, Miguel Martín, Marina Pollán
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: The Journal of Nutrition, Health and Aging, Vol 28, Iss 8, Pp 100312- (2024)
Druh dokumentu: article
ISSN: 1760-4788
DOI: 10.1016/j.jnha.2024.100312
Popis: Objectives: Adherence to healthy lifestyle recommendations has been reported to improve health-related quality of life (HRQL) in breast cancer (BC) patients, but the influence of long-term behavioral changes remains unknown. We evaluated the association between adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) cancer prevention recommendations and HRQL both, at BC diagnosis and the change 7−12 years later. Design: Prospective cohort study. Settings and participants: A total of 406 breast cancer survivors, from the EpiGEICAM study, were recruited in 16 Spanish hospitals. Measurements: Epidemiological, clinical, dietary, physical activity and HRQL information was collected both at recruitment and 7−12 years later. A 7-item score to measure compliance with recommendations was assessed according to the 2018 WCRF/AICR scoring criteria. HRQL was evaluated using SF-36 questionnaire. Linear mixed models for longitudinal data were used to assess the cross-sectional and longitudinal association between adherence score and the physical and mental component summary scores. Results: At diagnosis, for each unit increase in WCRF/AICR score adherence, the HRQL physical domain increased 0.78 points (95%CI: −0.04 to 1.60; P trend:0.06). The mean change in physical HRQL from diagnosis to follow-up per unit increase in within-subject adherence score was 0.73 points (95%CI: −0.18 to 1.65; P trend: 0.12). For the mental domain, no association was observed with compliance with the recommendations at diagnosis, nor with changes in adherence over time. Conclusions: Our results suggest that Increased adherence to WCRF/AICR cancer prevention recommendations over time could contribute to slightly improved long-term physical HRQoL in BC survivors.
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