1-[(1S,2S)-1,2-Bis(2-hydroxyphenyl)-2-pivaloylaminoethylamino]-2,2-dimethyl-1-propanone

Autor: Fulgentius Nelson Lugemwa
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Molbank, Vol 2019, Iss 1, p M1054 (2019)
Druh dokumentu: article
ISSN: 1422-8599
DOI: 10.3390/M1054
Popis: When 2-[(1S,2S)-1,2-diamino-2(2-hydroxyphenyl)ethyl]phenol (I) was reacted with 2 mole equivalents of trimethyl acetic (pivalic) anhydride in tetrahydrofuran at room temperature, 1-[(1S,2S)-1,2-bis(2-hydroxyphenyl)-2-pivaloylaminoethylamino]-2,2-dimethyl-1-propanone (II) was obtained quantitatively as the only product. The structure of the product was determined using 1H- and 13C-NMR. The COSY spectrum indicated that the single –NH was coupled to the single benzylic proton, –CH. The versality of the transformation could be used to generate additional compounds for use in various research areas.
Databáze: Directory of Open Access Journals
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