Inflammatory Markers and Incidence of other Autoimmune Diseases in Patients with Oral Lichen Planus

Autor: Ana Družijanić, Ana Glavina, Mirna Draganja, Dolores Biočina-Lukenda, Livia Cigić
Jazyk: English<br />Croatian
Rok vydání: 2019
Předmět:
Zdroj: Acta Stomatologica Croatica, Vol 53, Iss 4, Pp 363-370 (2019)
Druh dokumentu: article
ISSN: 0001-7019
1846-0410
DOI: 10.15644/asc53/4/7
Popis: Introduction: Oral lichen planus (OLP) is a chronic immune, inflammatory disease of the oral cavity of a still unknown etiology. Materials and methods: The study involved 63 subjects diagnosed with oral lichen planus and 63 subjects without pathologic changes in the oral mucosa who were classified as controls. All subjects were given a detailed medical history at first screening. The medical history of the presence of other autoimmune disease in all subjects was supported by medical records. A sample of venous blood was taken from each subject in order to determine sedimentation rate (SE) and leukocyte count (L) using standard laboratory procedures, and serum C-reactive protein (CRP) concentration values were determined as well. Statistical analysis: The methods of descriptive statistics, χ2-test, the Fisher’s exact test, and the Student’s t-test were used in the statistical processing of the results. The results were interpreted at a significance level of P
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