Sex-differential cognitive performance on MCCB of youth with BD-II depression

Autor: Dong Huang, Shunkai Lai, Shuming Zhong, Yiliang Zhang, Jiali He, Shuya Yan, Xiaosi Huang, Xiaodan Lu, Manying Duan, Kailin Song, Kaiwei Ye, Yandi Chen, Suiyi Ye, Jiankang Lai, Qilin Zhong, Xiaodong Song, Yanbin Jia
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Psychiatry, Vol 24, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 1471-244X
DOI: 10.1186/s12888-024-05701-7
Popis: Abstract Background Recent evidences have shown sex-differential cognitive deficits in bipolar disorder (BD) and differences in cognitions across BD subtypes. However, the sex-specific effect on cognitive impairment in BD subtype II (BD-II) remains obscure. The aim of the current study was to examine whether cognitive deficits differ by gender in youth with BD-II depression. Method This cross-sectional study recruited 125 unmedicated youths with BD-II depression and 140 age-, sex-, and education-matched healthy controls (HCs). The Chinese version of the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB) was used to assess cognitive functions. Mood state was assessed using the 24-item Hamilton Depression Rating Scale (24-HDRS) and the Young Mania Rating Scale (YMRS). Multivariate analysis of covariance (MANCOVA) was conducted. Result ​Compared with HCs, patients with BD-II depression had lower scores on MCCB composite and its seven cognitive domains (all p
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje