Pulmonary magnetic resonance imaging biomarkers of lung structure and function in adult survivors of bronchopulmonary dysplasia with COPD

Autor: Khadija Sheikh, Anurag Bhalla, Alexei Ouriadov, Heather M. Young, Cory M. Yamashita, Thuy Mai Luu, Sherri Katz, Grace Parraga
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Cogent Medicine, Vol 4, Iss 1 (2017)
Druh dokumentu: article
ISSN: 2331-205X
2331205X
DOI: 10.1080/2331205X.2017.1282033
Popis: Bronchopulmonary dysplasia (BPD) is an emerging risk factor for chronic obstructive pulmonary disease. For BPD survivors, there are no guidelines for the management of lung disease that is often misdiagnosed as asthma. Pulmonary magnetic resonsance imaging (MRI) provides clinically-relevant lung biomarkers of ventilation abnormalities and emphysema. Here our objective was to quantify lung MRI biomarkers in adults with BPD to understand the underlying pathophysiologies responsible for their symptoms and abnormal pulmonary-function. We hypothesized that MRI measurements would be abnormal and reflect emphysema, not airways disease. Patients aged 20–29 year and born ≤32 weeks gestational age were included and those with MRI contraindications were excluded. A 25-year-old female never-smoker born
Databáze: Directory of Open Access Journals
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