Derecruitment volume assessment derived from pressure–impedance curves with electrical impedance tomography in experimental acute lung injury

Autor: Xiu-Mei Sun, Guang-Qiang Chen, Yu-Mei Wang, Yi-Min Zhou, Jing-Ran Chen, Kun-Ming Cheng, Yan-Lin Yang, Lin-lin Zhang, Hong-Liang Li, Jian-Xin Zhou
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of International Medical Research, Vol 48 (2020)
Druh dokumentu: article
ISSN: 1473-2300
03000605
11608390
DOI: 10.1177/0300060520949037
Popis: Objective To investigate the accuracy of derecruitment volume (V DER ) assessed by pressure–impedance (P-I) curves derived from electrical impedance tomography (EIT). Methods Six pigs with acute lung injury received decremental positive end-expiratory pressure (PEEP) from 15 to 0 in steps of 5 cmH 2 O. At the end of each PEEP level, the pressure–volume (P-V) curves were plotted using the low constant flow method and release maneuvers to calculate the V DER between the PEEP of setting levels and 0 cmH 2 O (V DER-PV ). The V DER derived from P-I curves that were recorded simultaneously using EIT was the difference in impedance at the same pressure multiplied by the ratio of tidal volume and corresponding tidal impedance (V DER-PI ). The regional P-I curves obtained by EIT were used to estimate V DER in the dependent and nondependent lung. Results The global lung V DER-PV and V DER-PI showed close correlations (r = 0.948, P
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