Evaluating the Relationship between Plasma Chloride, Calcium and Interleukin-18 in Essential Hypertensive Subjects

Autor: O. O. Odewusi, O. A. Akindele, E. A. Omon, S. O. Obadire, A. A. Adesiyan, O. A. Ekundayo, K. D. Suleiman
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Applied Sciences and Environmental Management, Vol 28, Iss 11B Supplementary (2024)
Druh dokumentu: article
ISSN: 2659-1502
2659-1499
Popis: The mechanism underlying a persistent blood pressure elevation and its sequelae on the inflammatory cascades and electrolyte imbalance have not been fully elucidated. The objective of this study was to assess the relationship between plasma chloride (Cl), calcium (Ca) and interleukin-18 (IL-18) in essential hypertensive subjects in Ado-Ekiti, Ekiti state, Nigeria. The electrolytes, Ca, and IL-18 were determined using various standard method. Data obtained for BMI, blood pressure, IL-18 and electrolyte levels in treated and untreated essential hypertensive subjects were BMI (Kg/m2) 24.53±3.62; 26.76 ± 2.07; SBP (mmHg) 152.12±10.06; 156.54 ± 4.37; DBP (mmHg) 94.99 ± 4.81; 102.33 ± 6.21; IL-18 (pg/ml); 350.63 ± 82.17; 641.73 ± 69.66; Na (mmol/L); 139.75± 3.23; 150.15 ± 5.09; K (mmol/L) 3.97± 0.27; 3.34±0.31; Ca (mg/dl) 9.34± 0.62; 8.59 ± 0.33; and Cl (mmol/L) 113.62± 1.77; 104.22 ± 2.44 respectively. The BMI, SBP, DBP, IL-18 and Na were significantly higher (p
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