Co-existence of relapsing polychondritis and Crohn disease treated successfully with infliximab

Autor: Hye-In Jung, Hyun Jung Kim, Ji-Min Kim, Ju Yup Lee, Kyung Sik Park, Kwang Bum Cho, Yoo Jin Lee
Jazyk: English<br />Korean
Rok vydání: 2021
Předmět:
Zdroj: Yeungnam University Journal of Medicine, Vol 38, Iss 1, Pp 70-73 (2021)
Druh dokumentu: article
ISSN: 2384-0293
DOI: 10.12701/yujm.2020.00304
Popis: Relapsing polychondritis (RP) is a rare, progressive immune-mediated systemic inflammatory disease of unknown etiology, characterized by recurrent inflammation of cartilaginous structures. Approximately 30% of RP cases are associated with other autoimmune diseases. However, the co-occurrence of RP and Crohn disease (CD) has rarely been reported. Herein, we present a 35-year-old woman diagnosed with RP and CD, who was refractory to initial conventional medications, including azathioprine and glucocorticoid, but who subsequently responded to infliximab (IFX). For both diseases, remission was sustained with IFX. There has been no previous report regarding the successful treatment of co-existing RP and CD with IFX.
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