Influence of smoking and obesity on post-COVID-19 sequelae and risk of hospitalization

Autor: Daniel Fernández-Pedruelo, Raúl Juárez-Vela, Regina Ruiz de Viñaspre-Hernández, Javier Alonso-Alonso, José Maríal Criado-Gutiérrez, Consuelo Sancho-Sánchez
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Medicine, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2296-858X
DOI: 10.3389/fmed.2024.1499239
Popis: IntroductionThe COVID-19 pandemic, caused by the SARS-CoV-2 virus, has significantly impacted the global healthcare system, with particularly harmful effects on the human respiratory system. Beyond the acute symptoms, there is growing concern about persistent symptoms that last for weeks or months after the initial infection, known as long COVID syndrome. This study focuses on investigating the relationship between smoking, obesity, and the presence of post-COVID-19 sequelae, as well as their influence on the risk of hospitalization.Materials and methodsAn observational and retrospective study was conducted using medical records of patients diagnosed with COVID-19 in Castilla y León, Spain, between November 1 and 30, 2020. The patients were divided into three groups: smoking (current and former), obesity/overweight, and control group. Various variables were analyzed, including age, sex, and the presence of post-COVID-19 sequelae, chronic pathologies, cardiovascular diseases, psychological conditions, and hospitalization. Descriptive statistics and Odds Ratio analysis were used for comparisons.ResultsThe results revealed that obesity was significantly associated with a higher risk of post-COVID-19 sequelae, particularly memory disorders and neurological, mental, or psychological symptoms. In contrast, smoking was correlated with an increase in memory problems but did not show a direct influence on post-COVID-19 sequelae or hospitalization. Additionally, women were found to have a higher prevalence of obesity in the studied population.ConclusionThis study provides evidence that obesity increases the risk of post-COVID-19 sequelae, especially in terms of memory disorders and neuropsychological symptoms. On the other hand, smoking is related to memory problems. Regarding cardiovascular pathologies, there was not enough statistical evidence for analysis, while for hospitalization, it was determined that smoking and obesity do not have a direct influence on these post-COVID consequences.
Databáze: Directory of Open Access Journals