Relación entre la enzima convertidora de angiotensina, polimorfismo I/D, y obstrucción coronaria en una población del Quindío, Colombia
| Autor: | Patricia Landázuri, Hugo Castaño, Nelsy Loango, Andrea Cardona-Barreto, Alejandra María Giraldo |
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| Jazyk: | English<br />Spanish; Castilian |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Universitas Scientiarum, Vol 16, Iss 3, Pp 193-199 (2011) |
| Druh dokumentu: | article |
| ISSN: | 0122-7483 2027-1352 |
| Popis: | Relationship between angiotensin-converting enzyme, I/D polymorphism, and coronary obstruction in a population of Quindío,Colombia. Angiotensin-converting enzyme (ACE) activity in serum and insertion/deletion (I/D) polymorphism have been associated tocardiovascular disease in several studies. Objective. To find a relationship between ACE activity and I/D polymorphism in the enzymegene in patients with coronary obstruction revealed by angiography. Materials and methods. Sample comprised patients attending ahemodynamics center in Quindío in need of a coronary angiography. ACE activity was measured by spectrophotometry and the I/Dgenotype determined by polymerase chain reaction. Results. 542 patients were divided into two groups: individuals with coronaryobstruction higher than or equal to 50% (OC≥50) and individuals with coronary obstruction less than 50% (CO |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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