Kidney Transplantation in Patients With Active Multiple Myeloma: Case Reports

Autor: Erik Lawrence Lum, MD, Neil Kogut, MD, Thu Pham, MD, Gabriel M. Danovitch, MD, Suphamai Bunnapradist, MD
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Transplantation Direct, Vol 3, Iss 8, p e200 (2017)
Druh dokumentu: article
ISSN: 2373-8731
00000000
DOI: 10.1097/TXD.0000000000000716
Popis: Abstract. Kidney disease is a common complication in patients with multiple myeloma. Traditionally, patients with active multiple myeloma and end-stage renal disease have been excluded from kidney transplantation due to the risk of malignancy progression. The introduction of bortezomib-based therapy for patients with multiple myeloma and renal impairment has significantly improved survival in this population. In this report, we present 2 cases of patients with active and controlled multiple myeloma who underwent successful kidney transplantation without progression of their underlying malignancy. In patients with active multiple myeloma controlled with bortezomib, kidney transplantation should be considered a valid option for patients with end-stage kidney disease.
Databáze: Directory of Open Access Journals