| Autor: |
Nariman A. Helmy, Somia A. Eissa, Hossam H. Masoud, Assem F. Elessawy, Randa I. Ahmed |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Egyptian Journal of Chest Disease and Tuberculosis, Vol 61, Iss 4, Pp 371-375 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
0422-7638 |
| DOI: |
10.1016/j.ejcdt.2012.09.003 |
| Popis: |
Introduction: Tuberculosis (TB), the single most frequent infectious cause of death worldwide, also is a major cause of pleural effusion, which in TB usually has lymphocytic and exudative characteristics. Differential diagnosis between TB and nontuberculous pleural effusion can be sometimes difficult, representing a critically important clinical problem. Aim of the work: To evaluate the clinical utility of pleural IFN-γ level in pleural fluid for diagnosing tuberculous pleuritis. Subject and methods: The study was conducted in kasr El-Aini hospital, Cairo University in the period from January 2011 to January 2012. It was carried on 40 patients. The patients included in the study were classified into group І (included 20 cases with tuberculous pleural effusion) and group II (included 20 cases with non tuberculous pleural effusion). All patients were subjected for complete history taking and clinical examination, chest X-rays PA and lateral views, pleural fluid aspiration and analysis. Result: Our results demonstrate that the pleural fluid concentrations of ADA, INF-γ in patients with tuberculous pleural effusions are significantly higher than in other effusions. Most importantly, ROC analysis clearly demonstrated ADA to be more sensitive and specific than INF-γ for diagnosis of tuberculous pleuritis. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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