eGFRcystatinC/eGFRcreatinine ratio

Autor: Lauris Avotins, Juta Kroica, Aivars Petersons, Dace Zentina, Zaiga Kravale, Anna Saulite, Karlis Racenis
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Nephrology, Vol 24, Iss 1, Pp 1-8 (2023)
Druh dokumentu: article
ISSN: 1471-2369
DOI: 10.1186/s12882-023-03315-x
Popis: Abstract Background Shrunken Pore Syndrome (SPS), defined as a reduced ratio between two estimated filtration rates (based on cystatin C and creatinine) is an increasingly recognized risk factor for long-term mortality. Although some patients with other conditions might be erroneously identified as SPS. Our aim was to bring the focus on possible pathophysiologic mechanisms influencing the ratio in the setting of SARS-CoV-2 pneumonia and acute kidney injury. Methods A single-centered prospective cohort study was conducted to investigate biomarkers in symptomatic COVID-19 pneumonia patients admitted to a hospital in Latvia. Nineteen biomarkers were measured in blood and three in urine samples. Associations were sought between these biomarkers, chronic diseases and the estimated GFRcystatinC/eGFRcreatinine ratio
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