Study-based registers of randomized controlled trials: Starting a systematic review with data extraction or meta-analysis

Autor: Farhad Shokraneh, Clive Elliott Adams
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: BioImpacts, Vol 7, Iss 4, Pp 209-217 (2017)
Druh dokumentu: article
ISSN: 2228-5660
2228-5652
DOI: 10.15171/bi.2017.25
Popis: Introduction: Despite years of use of study-based registers for storing reports of randomized controlled trials (RCTs), the methodology used in developing such registers/databases has not been documented. Such registers are integral to the process of scientific reviewing. We document and discuss methodological aspects of the development and use of study-based registers. Although the content is focused on the study-based register of randomized/controlled clinical trials, this work applies to developers of databases of all sorts of studies related to the human, animals, cells, genes, and molecules. Methods: We describe necessity, rationale, and steps for the development, utilization and maintenance of study-based registers as well as the challenges and gains for the organizations supporting systematic reviews of the published and unpublished literature. Conclusion: The ultimate goal of having a study-based register is to facilitate efficient production of systematic reviews providing rapid, yet accurate, evidence for the decision-makers. We argue that moving towards study-based registers is an inevitable welcome direction and that infrastructures are ready for such movement.
Databáze: Directory of Open Access Journals